产品货号：
Z19981
中文名称：
LRRK2抗体
英文名称：
Anti-LRRK2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LRRK2 Antibody |
| 指标别名 | leucine rich repeat kinase 2;AURA17;DARDARIN;PARK8;RIPK7;ROCO2;LRRK2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | LRRK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human LRRK2 recombinant protein (Position:E10-L350).Human LRRK2 shares 82% amino acid (aa) sequence identity with mouse LRRK2. |
| 实际分子量 | 286KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Leucine-rich repeat kinase 2 (LRRK2),also known as dardarin,is anenzyme that in humans is encoded by the PARK8 gene.It is a member of the leucine-rich repeat kinase family.This gene is mapped to 12q12.The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.Expression of mutant LRRK2 induced apoptotic cell death in neuroblastoma cells and in mouse cortical neurons.It has been determined that LRRK2 possesses mixed-lineage kinase activity,and LRRK2 also showed autophosphorylation activity.What’s more,LRRK2 has an affinity for lipids or lipid-associated proteins and may play a role in the biogenesis or regulation of membranous intracellular structures in the brain.It is also an IFNG target gene that may be involved in signaling pathways relevant to Crohn disease. |
| Uniprot ID | Q5S007 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | leucine-rich repeat kinase 2 |
| 蛋白名全称 | Leucine-rich repeat serine/threonine-protein kinase 2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：LRRK2抗体，LRRK2多抗，Anti-LRRK2 Antibody